Emin Gun Sirer

Avalanche: sub-second finality L1, $1B+ TVL

Co-founder and CEO of Ava Labs — the company behind Avalanche. Cornell professor and one of the most cited distributed systems researchers in crypto. Avalanche introduced the novel consensus mechanism achieving sub-second finality at scale. Building AvaCloud and Evergreen Subnets for institutional blockchain deployments. Known for proposing selfish mining attack on Bitcoin in 2013.

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Avalanche● activeEthereum

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Jansen Teng@ethermage

Virtuals Protocol: $100M+ market cap; 18,000+ tokenized agents; Eastworld Labs

Co-founder and CEO of Virtuals Protocol — the leading AI agent launchpad on Base. Over 18,000 tokenized agents deployed across Base, Solana, Ethereum, Ronin, and Arbitrum. $7B+ in cumulative trading volume. Launched Agent Commerce Protocol (ACP) for agent-to-agent transactions. Launched Eastworld Labs in Feb 2026 — an AI accelerator to bring humanoid robots onchain. Evolved from PathDAO, a gaming guild that raised $16M.

AIBase

Raullen Chai@raullen

10M+ connected devices, $100M+ raised

Co-founder and CEO of IoTeX — the leading blockchain platform for DePIN (Decentralized Physical Infrastructure Networks) and Physical AI. Connecting real-world devices and sensor data to blockchains. Partnerships with Google, Samsung, and ARM. Pioneered the ioID device identity standard. Building infrastructure for autonomous vehicles, robotics, and smart cities. $50M raised. PhD in cryptography from University of Waterloo, prev Google and Uber.

EthereumAIDePIN

Alex Cheema@alexocheema

Exo Labs: run Llama 405B across Mac Minis, endorsed by Karpathy, open source distributed AI inference

Co-founder of Exo Labs — the open source framework that lets anyone run large AI models across multiple consumer devices instead of expensive GPU clusters. Oxford physics graduate who previously worked in distributed systems for web3. Mentioned by Karpathy for enabling LLM inference on consumer hardware.